Bond is interesting as the character should presumably either remain era-appropriate or the movies should become period pieces, (Neither of which specify or prevent changing casting around.) The Bond movies have changed quite a bit over the eras and I feel like anyone trying to make them into a single continuity is going to lose a lot of sleep. I feel like the “periodically replaced” does work, with the possible exception that the current one is coincidentally named Bond as well somehow.
As for pregnant Time Lords: They’re human-looking aliens, but aliens. Maybe the babies pop out like baby marsupials, or are rarely if ever at the pain threshold to trigger a regeneration.
(An amusing image is a Time Lord who regenerates at a surprisingly low pain threshhold, like stubbing one’s toe, stepping on a Lego, bee sting, hang nails, etc…)